Our Infrastructure

JSNC's researchers have expertise in a wide variety of laboratory assays and working with specimens of many types and origins (human postmortem brain samples and mouse/rat brains - freshly frozen or fixated, serums, DNA extracts, etc.).

Our laboratory infrastructures include:

• Animal behavior (cognitive assessments are performed in a designated room, equipped with video tracking hardware and compatible software)

•  Cell cultures

• Cryostat microtome (cryochamber temperature 0°C to -35°C; section thickness 1-60 µm)

• Electrophoresis

•  Enzyme-linked immunosorbent assay (ELISA)

• Fluorescence microscope

• Genotyping

• Immunohistochemistry (IHC), including immunofluorescence

•  PCR

• Protein immunoblotting (Western blot)

The JSNC collaborates, on everyday-basis, with numerous departments and labs within the Sheba Medical Center. This allows the JSNC the availability of a wide variety of advanced research techniques and pools of clinical materials.

Collaborations with Clinical Departments

•  Cardiology

• Geriatrics

•  Internal Medicine

• Neurology

• Neurosurgery

• Psychiatry

• Radiology

• Rehabilitation

Collaboration with Research Labs/Facilities

• Animal Facility (rodents housing and care in an SPF-ready facility)

• Cancer (e.g. cell cultures, genomic analyses, bioinformatics, stem-cells)

• Endocrinology (routine and specially-designed lab work)

• Genetics

• Imaging (including MRI, fMRI, CT, PET, SPECT)
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• Immunology

• Lipids (research of cardio-vascular related factors of disease)

• Pathology (routine and specially-designed histochemistry stains)